Overview of what we do

The Rona lab seeks to gain a better understanding of the fundamental processes that maintain genomic integrity within our cells. It is remarkable how information encoded in our genome is maintained with unparalleled precision, yet at the same time is flexible enough to be able to adapt to environmental changes. DNA repair processes are crucial aspects of biology as mis-regulation of these mechanisms are often the driving force behind several types of cancer and neurodegenerative diseases. By unraveling the underlying molecular mechanisms of these diseases, we aim to provide the foundation of novel therapeutic approaches. In our work we rely on genetic, biochemical, and proteomic approaches in mammalian cells as well as collaborations with structural biologists and mouse geneticists. To learn more about our current efforts click on the research areas listed below.

Created in BioRender. Rona, G. (2025) https://BioRender.com/b49g378