Key Research Articles

  • Rona, G., Miwatani-Minter, B., Zhang, Q., Goldberg, H. V., Kerzhnerman, M. A., Howard, J. B., Simoneschi, D., Lane, E., Hobbs, J. W., Sassani, E., Wang, A. A., Keegan, S., Laverty, D. J., Piett, C. G., Pongor, L. S., Xu, M. L., Andrade, J., Thomas, A., Sicinski, P., Askenazi, M., Ueberheide, B., Fenyö, D., Nagel, Z. D. & Pagano, M. CDK-independent role of D-type cyclins in regulating DNA mismatch repair. Mol Cell (2024).

  • Zhang, Q., Kerzhnerman, M. A., García-Vázquez, N., Rona, G. Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle. J. Vis. Exp (2023).

  • Rona, G., Zeke, A., Miwatani-Minter, B., de Vries, M., Kaur, R., Schinlever, A., Garcia, S. F., Goldberg, H. V., Wang, H., Hinds, T. R., Bailly, F., Zheng, N., Cotelle, P., Desmaele, D., Landau, N. R., Dittmann, M. & Pagano, M. The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target. Cell Death Differ 29, 285-292 (2022).

  • Simoneschi, D., Rona, G., Zhou, N., Jeong, Y. T., Jiang, S., Milletti, G., Arbini, A. A., O'Sullivan, A., Wang, A. A., Nithikasem, S., Keegan, S., Siu, Y., Cianfanelli, V., Maiani, E., Nazio, F., Cecconi, F., Boccalatte, F., Fenyo, D., Jones, D. R., Busino, L. & Pagano, M. CRL4(AMBRA1) is a master regulator of D-type cyclins. Nature 592, 789-793 (2021).

  • Miwatani-Minter, B. & Rona, G. Laser Micro-Irradiation to Study DNA Recruitment During S Phase. J Vis Exp (2021).

  • Maiani, E., Milletti, G., Nazio, F., Holdgaard, S. G., Bartkova, J., Rizza, S., Cianfanelli, V., Lorente, M., Simoneschi, D., Di Marco, M., D'Acunzo, P., Di Leo, L., Rasmussen, R., Montagna, C., Raciti, M., De Stefanis, C., Gabicagogeascoa, E., Rona, G., Salvador, N., Pupo, E., Merchut-Maya, J. M., Daniel, C. J., Carinci, M., Cesarini, V., O'Sullivan, A., Jeong, Y. T., Bordi, M., Russo, F., Campello, S., Gallo, A., Filomeni, G., Lanzetti, L., Sears, R. C., Hamerlik, P., Bartolazzi, A., Hynds, R. E., Pearce, D. R., Swanton, C., Pagano, M., Velasco, G., Papaleo, E., De Zio, D., Maya-Mendoza, A., Locatelli, F., Bartek, J. & Cecconi, F. AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature 592, 799-803 (2021).

  • Palinkas, H. L., Bekesi, A., Rona, G., Pongor, L., Papp, G., Tihanyi, G., Holub, E., Poti, A., Gemma, C., Ali, S., Morten, M. J., Rothenberg, E., Pagano, M., Szuts, D., Gyorffy, B. & Vertessy, B. G. Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments. Elife 9 (2020).

  • Rona, G., Roberti, D., Yin, Y., Pagan, J. K., Homer, H., Sassani, E., Zeke, A., Busino, L., Rothenberg, E. & Pagano, M. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. Elife 7 (2018).

  • Rona, G., Scheer, I., Nagy, K., Palinkas, H. L., Tihanyi, G., Borsos, M., Bekesi, A. & Vertessy, B. G. Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications. Nucleic Acids Res 44, e28 (2016).

  • Dankert, J. F., Rona, G., Clijsters, L., Geter, P., Skaar, J. R., Bermudez-Hernandez, K., Sassani, E., Fenyo, D., Ueberheide, B., Schneider, R. & Pagano, M. Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2. Mol Cell 64, 507-519 (2016).

  • Rona, G., Borsos, M., Ellis, J. J., Mehdi, A. M., Christie, M., Kornyei, Z., Neubrandt, M., Toth, J., Bozoky, Z., Buday, L., Madarasz, E., Boden, M., Kobe, B. & Vertessy, B. G. Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation. Cell Cycle 13, 3551-3564 (2014).

  • Muha, V., Horvath, A., Bekesi, A., Pukancsik, M., Hodoscsek, B., Merenyi, G., Rona, G., Batki, J., Kiss, I., Jankovics, F., Vilmos, P., Erdelyi, M. & Vertessy, B. G. Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement. PLoS Genet 8, e1002738 (2012).